Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645248 | 1.00 | NOTUM (0.45) | NOTUMMMP8HDAC9ALDH1A1HSD17B3 | |
| SCHEMBL8067852 | 0.87 | NOTUM (0.39) | NOTUMMMP8HDAC9ALDH1A1HSD17B3 | |
| SCHEMBL9770095 | 0.80 | BRD4 (0.50) | ALDH1A1NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL8114506 | 0.79 | NOTUM (0.43) | NOTUMHDAC9ALDH1A1HSD17B3NPC1 | |
| SCHEMBL30863938 | 0.78 | MMP8 (0.47) | NOTUMMMP8HDAC9ALDH1A1POLB | |
| SCHEMBL1014144 | 0.78 | MMP8 (0.47) | NOTUMMMP8HDAC9ALDH1A1POLB | |
| SCHEMBL12571286 | 0.77 | NOTUM (0.42) | NOTUMHDAC9ALDH1A1HSD17B3NPC1 | |
| SCHEMBL12203632 | 0.76 | MEN1 (0.44) | NOTUMMMP8HDAC9ALDH1A1POLB | |
| SCHEMBL12373447 | 0.76 | HDAC9 (0.42) | NOTUMHDAC9ALDH1A1HSD17B3NPC1 | |
| SCHEMBL10876485 | 0.74 | MEN1 (0.40) | NOTUMMMP8HDAC9ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186010-A | Synthesis method of atimetazole hydrochloride | 厦门欧瑞捷生物科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-112225700-B | Preparation method of atemezole | 湖南新合新生物医药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-112225700-A | Preparation method of altimezole | 湖南新合新生物医药有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-111925330-A | Preparation method of altimezole | 上海阿达玛斯试剂有限公司 | 2020-11-13 | — | — | CN | disclosed |
| JP-2000256236-A | PRODUCTION OF OPTICALLY ACTIVE ALCOHOL COMPOUND | SUMITOMO CHEM CO LTD | 2000-09-19 | — | — | JP | disclosed |