Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355764 | 0.80 | PDPK1 (0.55) | EGFRPDPK1CYP2A6CYP1A1CYP1A2 | |
| SCHEMBL15606528 | 0.80 | PDPK1 (0.58) | EGFRPDPK1CYP2A6CYP1A1CYP1A2 | |
| SCHEMBL13994026 | 0.77 | PDPK1 (0.50) | EGFRPDPK1CYP2A6CYP1A1CYP1A2 | |
| SCHEMBL5216527 | 0.77 | EGFR (0.52) | EGFRPDPK1CYP2A6CYP1A1CYP1A2 | |
| SCHEMBL30849066 | 0.76 | EGFR (0.55) | EGFRPDPK1CYP2A6CYP1A1CYP1A2 | |
| SCHEMBL15805858 | 0.76 | PDPK1 (0.72) | EGFRPDPK1CYP2A6SMPD3ADRB2 | |
| SCHEMBL8083581 | 0.75 | PRMT6 (0.48) | CYP2A6 | |
| SCHEMBL8078588 | 0.75 | PRMT6 (0.48) | CYP2A6KAT6A | |
| SCHEMBL29462071 | 0.74 | DYRK1A (0.57) | PDPK1CYP2A6CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1980934 | 0.74 | DYRK1A (0.57) | PDPK1CYP2A6CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836596-B1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0836596-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002257-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-01-23 | — | — | WO | disclosed |