SCHEMBL8078463

SCHEMBL8078463

COCCCCCCCCCN

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA3 P07451 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.50
BLM P54132 1/20 0.50
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
EPHX1 P07099 1/20 0.45
NFKB1 P19838 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921144 1.00
SCHEMBL8069136 1.00 DNM1 (0.50) DNM1CA12CA1CA2CA3
SCHEMBL9308087 1.00 DNM1 (0.50) DNM1CA12CA1CA2CA3
SCHEMBL8076688 1.00 DNM1 (0.50) DNM1CA12CA1CA2CA3
SCHEMBL8083458 1.00
SCHEMBL7989464 1.00 DNM1 (0.50) DNM1CA12CA1CA2CA3
SCHEMBL1579993 1.00 DNM1 (0.50) DNM1CA12CA1CA2CA3
SCHEMBL11644266 1.00 DNM1 (0.50) DNM1CA12CA1CA2CA3
SCHEMBL11652315 1.00 DNM1 (0.50) DNM1CA12CA1CA2CA3
Hydrochloric Acid SCHEMBL3508306 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024140595-A1 TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 珂阑(上海)医药科技有限公司 2024-07-04 WO disclosed
CN-118255685-A Tricyclic compound, pharmaceutical composition and application thereof 珂阑(上海)医药科技有限公司 2024-06-28 CN disclosed
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
EP-3548492-B1 CELL IMPERMEABLE COELENTERAZINE ANALOGUES PROMEGA CORP (US) 2023-07-05 EP disclosed
CN-113574041-A Method for producing bisphenol and method for producing polycarbonate resin 三菱化学株式会社 2021-10-29 CN disclosed
WO-2020189201-A1 METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-24 WO disclosed
EP-2708529-B1 METHOD FOR MANUFACTURING PARTICLES SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9796831-B2 Process for producing particles SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-24 US disclosed
US-9011920-B2 Transport-mediating colloidal pharmaceutical compounds B. BRAUN MELSUNGEN AG (DE) 2015-04-21 US disclosed
EP-2708529-A1 METHOD FOR MANUFACTURING PARTICLES Sumitomo Chemical Company Limited (JP) 2014-03-19 EP disclosed
US-20140065337-A1 PROCESS FOR PRODUCING PARTICLES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-06 US disclosed
US-20110237657-A1 Transport-Mediating Colloidal Pharmaceutical Compounds B. BRAUN MELSUNGEN AG (DE) 2011-09-29 US disclosed
EP-0846679-B1 Process for preparing 1,3-disubstituted urea SUMIKA FINE CHEMICALS CO LTD (JP) 2000-09-06 EP disclosed
US-5902899-A Process for preparing 1, 3-disubstituted urea SUMIKA FINE CHEMICALS CO., LTD. (JP) 1999-05-11 US disclosed
EP-0846679-A2 Process for preparing 1,3-disubstituted urea SUMIKA FINE CHEMICALS Co., Ltd. (JP) 1998-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237657-A1 Transport-Mediating Colloidal Pharmaceutical Compounds ABCB11, SLCO1B1, SLCO4C1 DNM1 2096/4885CA12 862/4885CA1 3082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.