Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 11/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085454 | 1.00 | SLC6A9 (0.33) | SLC6A9SLC6A5SIGMAR1 | |
| SCHEMBL8091606 | 0.82 | OPRD1 (0.34) | — | |
| SCHEMBL8098119 | 0.82 | OPRD1 (0.34) | — | |
| SCHEMBL13970161 | 0.80 | SLC6A9 (0.31) | SLC6A9SLC6A5 | |
| SCHEMBL3708336 | 0.77 | SLC6A9 (0.53) | SLC6A9SLC6A5 | |
| SCHEMBL4192554 | 0.77 | SLC6A9 (0.53) | SLC6A9SLC6A5 | |
| SCHEMBL4192550 | 0.77 | SLC6A9 (0.53) | SLC6A9SLC6A5 | |
| SCHEMBL13970253 | 0.75 | SLC6A9 (0.40) | SLC6A9SLC6A5 | |
| SCHEMBL8080629 | 0.75 | SLC6A9 (0.40) | SLC6A9SLC6A5 | |
| SCHEMBL13970169 | 0.75 | SLC6A9 (0.40) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013535-A1 | 2-AZABICYCLO(2.2.2)OCTANE DERIVATIVES AS MODULATORS OF THE GLYCINE TRANSPORTER I RECEPTOR | ASTRAZENECA AB (SE) | 2009-01-29 | — | — | WO | disclosed |