Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11191431 | 0.91 | LMNA (0.46) | LMNAALDH1A1TSHRCASP1CYP1A2 | |
| Alcohol SCHEMBL25309953 | 0.88 | HSP90AA1 (0.52) | LMNAALDH1A1TSHRCASP1CYP1A2 | |
| Alcohol SCHEMBL9588110 | 0.88 | LMNA (0.44) | LMNAALDH1A1TSHRCASP1CYP1A2 | |
| SCHEMBL10800782 | 0.85 | CASP1 (0.47) | LMNAALDH1A1CASP1CYP1A2SMN1; SMN2 | |
| SCHEMBL28235429 | 0.81 | CASP1 (0.45) | LMNAALDH1A1TSHRCASP1CYP1A2 | |
| Ethylamine SCHEMBL23925800 | 0.81 | CASP1 (0.45) | LMNACASP1CYP1A2HSP90AA1SMN1; SMN2 | |
| Butane SCHEMBL23581974 | 0.81 | CASP1 (0.45) | LMNACASP1CYP1A2HSP90AA1SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL8570947 | 0.81 | CASP1 (0.45) | LMNAALDH1A1TSHRCASP1CYP1A2 | |
| Methyl Alcohol SCHEMBL1535535 | 0.81 | LMNA (0.53) | LMNAALDH1A1CASP1CYP1A2HSP90AA1 | |
| Methyl Alcohol SCHEMBL7168433 | 0.81 | LMNA (0.53) | LMNAALDH1A1CASP1CYP1A2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777548-B | Modified flame retardant for high polymer material and preparation method thereof | 科迈特新材料有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117985758-A | V (V)2O3Preparation method of/C water-based zinc ion battery electrode material | 齐鲁工业大学(山东省科学院) | 2024-05-07 | — | — | CN | claimed |
| CN-117965077-A | Preparation method of melamine modified graphene oxide anticorrosive paint | 内蒙古大学 | 2024-05-03 | — | — | CN | claimed |
| CN-117801504-A | Boron-silicon synergistic MCA@ADP intumescent flame retardant TPU composite material and preparation method thereof | 常州大学 | 2024-04-02 | — | — | CN | claimed |
| CN-117777548-A | Modified flame retardant for high polymer material and preparation method thereof | 科迈特新材料有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117543161-A | High-flame-retardance diaphragm for lithium ion battery and preparation method of high-flame-retardance diaphragm | 江苏玖兴新材料科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-117327347-A | Flame-retardant polypropylene and preparation method and application thereof | 江苏海聚新材料科技有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-115160523-B | Low-temperature-brittleness-resistant modified melamine resin and preparation method thereof | 浙江亚迪纳新材料科技股份有限公司 | 2023-09-22 | — | — | CN | claimed |
| CN-116726867-A | Iron-nitrogen co-doped carbon composite material and preparation method and application thereof | 同济大学 | 2023-09-12 | — | — | CN | claimed |
| CN-116162343-A | Melamine cyanurate coated diethyl phosphinate aluminum intumescent flame retardant thermoplastic polyurethane and preparation method thereof | 常州大学 | 2023-05-26 | — | — | CN | claimed |
| CN-115197591-A | Visible light catalytic composite material and preparation method thereof | 天津市职业大学 | 2022-10-18 | — | — | CN | claimed |
| CN-115160523-A | Low-temperature-brittleness-resistant modified melamine resin and preparation method thereof | 浙江亚迪纳新材料科技股份有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-114196241-A | Photocatalytic self-cleaning coating and preparation method and application thereof | 天津市职业大学 | 2022-03-18 | — | — | CN | claimed |
| CN-113321192-B | Preparation method and application of cubic molybdenum nitride | 湖北工程学院 | 2022-02-08 | — | — | CN | claimed |
| CN-113321192-A | Preparation method and application of cubic molybdenum nitride | 湖北工程学院 | 2021-08-31 | — | — | CN | claimed |
| CN-109183409-B | Method for preparing flame-retardant viscose fiber from melamine grafted oxidized viscose fiber and flame-retardant viscose fiber | 重庆消防安全技术研究服务有限责任公司 | 2020-10-13 | — | — | CN | claimed |
| CN-109748590-A | A kind of g-C3N4The preparation method of composite ceramics bonding agent | 河南工业大学 | 2019-05-14 | — | — | CN | claimed |
| CN-109183409-A | The method and flame retardant viscose fiber of melamine grafting oxidation viscose rayon preparation flame retardant viscose fiber | 重庆消防安全技术研究服务有限责任公司 | 2019-01-11 | — | — | CN | claimed |
| CN-103275390-A | Polypropylene-containing composition and preparation method thereof | SHENHUA GROUP CORP LTD | 2013-09-04 | — | — | CN | claimed |
| CN-103144275-A | Stabilizing treatment method for polyformaldehyde | SHENHUA GROUP CORP LTD | 2013-06-12 | — | — | CN | claimed |