SCHEMBL8078669

SCHEMBL8078669

CC(NC(N)=O)C(C)(C)NC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
THPO P40225 1/20 0.33
PIK3CD O00329 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2690051 0.78 PIK3CD (0.50) POLBNPC1ALDH1A1CYP1A2TSHR
SCHEMBL4850022 0.78 CYP3A4 (0.44) POLBNPC1ALDH1A1CYP1A2TSHR
SCHEMBL8499109 0.74 PIK3CD (0.38) POLBPIK3CD
SCHEMBL20715752 0.74 PIK3CD (0.38) POLBPIK3CD
SCHEMBL6209376 0.73 CRBN (0.32) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL14334777 0.71 NPC1 (0.35) NPC1ALDH1A1CYP1A2TSHRNFKB1
SCHEMBL29723722 0.71 NPC1 (0.35) NPC1ALDH1A1CYP1A2TSHRNFKB1
SCHEMBL27264712 0.70 POLB (0.35) POLBALDH1A1NFKB1THPOPIK3CD
SCHEMBL27832426 0.70 CAD (0.33) NPC1ALDH1A1TSHRNFKB1LMNA
SCHEMBL2108767 0.69 CAD (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6074757-A APPLYING POLYAMIDOCARBOXYLIC ACIDS AND ONE OR MORE DIAMINES AND ONE OR MORE TETETRACARBOXYLIC DIESTER TO A SUBSTRATE TO FORM A COATED SUBSTRATE AND CURING TO FORM A CURED FILM OF POLYAMIDEIMIDE COPOLYMER SCHENECTADY EUROPE GMBH (DE) 2000-06-13 US disclosed
US-5493003-A MIXTURES OF AMINES, AMIDES AND/OR ESTERS OF TETRACARBOXYLIC ACIDS HAVING AMIDO OR ESTER GROUPS SUBSTITUTED WITH CARBOXYL, SULFO, SILYL OR SILOXY GROUPS, ELECTRONICS BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1996-02-20 US disclosed
US-5489644-A COMPRISING AROMATIC DIAMINES AND TETRAESTER OF AROMATIC TETRACARBOXYLIC ACID; PROTECTIVE COATING FOR METALS, SILICON WAFERS, GLASS BASF LACKE + FARBEN (DE) 1996-02-06 US disclosed
US-5478917-A Aromatic polyamines, tetracarboxylic acid amides and esters; smoothness, flexibility BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1995-12-26 US disclosed
US-5332799-A Aromatic diamines, diesters of aromatic tetracarboxylic acids, circuit coatings BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1994-07-26 US disclosed
US-5264545-A Aromatic or partly aromatic diamine with tetracarboxylic acid BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1993-11-23 US disclosed