Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715752 | 0.81 | PIK3CD (0.38) | PIK3CDPOLBDPP4 | |
| SCHEMBL2690051 | 0.80 | PIK3CD (0.50) | PIK3CDPOLB | |
| SCHEMBL6209376 | 0.75 | CRBN (0.32) | PIK3CD | |
| SCHEMBL8078669 | 0.74 | POLB (0.34) | PIK3CDPOLB | |
| SCHEMBL8633017 | 0.70 | PIK3CD (0.35) | PIK3CDPOLB | |
| SCHEMBL24700130 | 0.70 | MMP8 (0.35) | PIK3CDPOLB | |
| SCHEMBL13209005 | 0.70 | TSHR (0.45) | PIK3CDPOLB | |
| SCHEMBL13209006 | 0.70 | TSHR (0.45) | PIK3CDPOLB | |
| SCHEMBL13209014 | 0.70 | TSHR (0.45) | PIK3CDPOLB | |
| SCHEMBL21048956 | 0.69 | GRIK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586663-B1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LTD (GB) | 1999-09-29 | — | — | EP | disclosed |
| US-5519015-A | BACTERICIDES | ZENECA LIMITED (GB) | 1996-05-21 | — | — | US | disclosed |
| EP-0586663-A1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LIMITED (GB) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993019070-A1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |