Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198008 | 0.83 | KDM4E (0.36) | P2RX7LMNA | |
| SCHEMBL6886488 | 0.78 | P2RX7 (0.36) | SMN1; SMN2ALDH1A1P2RX7 | |
| SCHEMBL2068597 | 0.70 | — | — | |
| SCHEMBL29364216 | 0.65 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1P2RX7 | |
| SCHEMBL335305 | 0.65 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1P2RX7 | |
| SCHEMBL30590435 | 0.63 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1P2RX7 | |
| SCHEMBL2068646 | 0.62 | — | — | |
| SCHEMBL3408658 | 0.62 | — | — | |
| SCHEMBL3514747 | 0.61 | MAPK1 (0.36) | HTT | |
| SCHEMBL70978 | 0.61 | P2RX7 (0.61) | SMN1; SMN2ALDH1A1P2RX7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048880-A | THERAPY FOR CYTOKINE SENSITIVE DISEASES | PFIZER PHARAMACEUTICALS INC. (JP) | 2000-04-11 | — | — | US | disclosed |