SCHEMBL8078731

SCHEMBL8078731

Cc1cc2c(cc1C)C([Zr](Cl)(Cl)C1C(c3ccccc3)=Cc3cc(C)c(C)cc31)C(c1ccccc1)=C2

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1681584 0.78
SCHEMBL8079661 0.76 LMNA (0.34)
SCHEMBL27508402 0.76 NPC1 (0.30) ESR2
SCHEMBL6287549 0.76 CYP1A2 (0.33)
SCHEMBL6287249 0.74 RGS4 (0.31)
Hydrochloric Acid SCHEMBL8078727 0.73 KDM4E (0.33)
SCHEMBL6290299 0.72 TACR1 (0.32)
SCHEMBL8080014 0.71
SCHEMBL7641274 0.69
SCHEMBL6927240 0.69 CNR1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745099-B1 REACTOR BLEND POLYPROPYLENE AND PROCESS FOR THE PREPARATION THEREOF MONTELL TECHNOLOGY COMPANY BV (NL) 2000-09-13 EP disclosed
US-6107431-A CATALYTIC POLYMERIZATION OF POLYPROPYLENE THERMOPLASTIC ELASTOMER USING ALUMOXANE-METALLOCENE DERIVATIVE CATALYST MONTELL TECHNOLOGY COMPANY BV (NL) 2000-08-22 US disclosed
US-5747621-A CATALYTIC ADDITION POLYMERIZATION MONTELL TECHNOLOGY COMPANY BV (NL) 1998-05-05 US disclosed
EP-0745099-A1 REACTOR BLEND POLYPROPYLENE, PROCESS FOR THE PREPARATION THEREOF AND PROCESS FOR PREPARING METALLOCENE LIGANDS Montell Technology Company bv (NL) 1996-12-04 EP disclosed
WO-1996020225-A2 REACTOR BLEND POLYPROPYLENE, PROCESS FOR THE PREPARATION THEREOF AND PROCESS FOR PREPARING METALLOCENE LIGANDS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1996-07-04 WO disclosed