SCHEMBL8078751

SCHEMBL8078751

CCc1ccc(N(c2ccc(CO)cc2)c2ccc(-c3ccc(N(c4ccc(CC)cc4)c4ccc(CO)cc4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.43
LIPG Q9Y5X9 1/20 0.43
EGFR P00533 1/20 0.41
MKNK1 Q9BUB5 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
HRH3 Q9Y5N1 3/20 0.39
NISCH Q9Y2I1 1/20 0.38
ALDH1A1 P00352 1/20 0.38
UCHL1 P09936 1/20 0.37
KIF11 P52732 1/20 0.37
S1PR1 P21453 1/20 0.37
S1PR5 Q9H228 1/20 0.37
APP P05067 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13599818 1.00 LPL (0.43) LPLLIPGEGFRMKNK1MKNK2
SCHEMBL13818938 1.00 LPL (0.43) LPLLIPGEGFRMKNK1MKNK2
SCHEMBL15468969 0.94 LPL (0.48) LPLLIPGALDH1A1TSHRMAPK1
SCHEMBL14357626 0.93 MEN1 (0.45) LPLLIPGMKNK1MKNK2ALDH1A1
SCHEMBL13599813 0.91 MKNK1 (0.45) MKNK1MKNK2HRH3KIF11APP
SCHEMBL22941869 0.91 MKNK1 (0.45) MKNK1MKNK2HRH3KIF11APP
SCHEMBL309287 0.91 MKNK1 (0.45) MKNK1MKNK2HRH3KIF11APP
SCHEMBL4623255 0.89 EGFR (0.48) LPLLIPGEGFRMKNK1MKNK2
SCHEMBL919282 0.89 HRH3 (0.46) LPLLIPGEGFRHRH3NISCH
SCHEMBL10062463 0.89 HRH3 (0.46) LPLLIPGEGFRHRH3NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710893-B1 Charge transporting polymer, process for producing the same, and electrophotographic photoreceptor containing the same FUJI XEROX CO LTD (JP) 2000-08-23 EP disclosed
US-5734003-A INTERMOLECULAR CONDENSATION OF CHARGE TRANSPORTING COMPOUND HAVING HYDROXYL GROUPS; EXCELLENT SOLUBILITY, FILM FORMING, STRENGTH AND STABILITY TO REPEATED USE FUJI XEROX CO., LTD. (JP) 1998-03-31 US disclosed
US-5639581-A ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI XEROX CO., LTD. (JP) 1997-06-17 US disclosed
EP-0710893-A1 Charge transporting polymer, process for producing the same, and organic electronic device containing the same FUJI XEROX CO., LTD. (JP) 1996-05-08 EP disclosed