SCHEMBL919282

SCHEMBL919282

CCc1ccc(N(c2ccc(CC)cc2)c2ccc(-c3ccc(N(c4ccc(CC)cc4)c4ccc(CC)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.46
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
NISCH Q9Y2I1 1/20 0.44
TP53 P04637 2/20 0.43
EGFR P00533 1/20 0.43
TSHR P16473 2/20 0.43
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
UCHL1 P09936 1/20 0.42
TAAR1 Q96RJ0 2/20 0.42
CYP2A6 P11509 1/20 0.41
METAP2 P50579 1/20 0.41
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10062463 1.00 HRH3 (0.46) HRH3LPLLIPGNISCHTP53
SCHEMBL13700812 0.93 HRH3 (0.41) HRH3LPLLIPGNISCHTP53
SCHEMBL9159692 0.93 HRH3 (0.41) HRH3LPLLIPGNISCHTP53
SCHEMBL3896543 0.92 LPL (0.52) LPLLIPGTP53TSHRMAPK1
SCHEMBL12304289 0.92 LPL (0.52) LPLLIPGTP53TSHRMAPK1
SCHEMBL12533875 0.91 HCRTR2 (0.41) HRH3LPLLIPGNISCHTP53
SCHEMBL12799485 0.91 TP53 (0.54) HRH3LPLLIPGNISCHTP53
SCHEMBL17735812 0.91 HCRTR2 (0.41) HRH3LPLLIPGNISCHTP53
SCHEMBL13241993 0.91 HCRTR2 (0.41) HRH3LPLLIPGNISCHTP53
SCHEMBL13152312 0.91 HCRTR2 (0.41) HRH3LPLLIPGNISCHTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960082-B2 Photoreceptor protective overcoat layer including silicone polyether and method of making same XEROX CORPORATION (US) 2011-06-14 US claimed
US-20100068636-A1 PHOTORECEPTOR PROTECTIVE OVERCOAT LAYER INCLUDING SILICONE POLYETHER AND METHOD OF MAKING SAME XEROX CORPORATION (US) 2010-03-18 US claimed
US-20090130575-A1 PHOTORECEPTOR XEROX CORPORATION (US) 2009-05-21 US claimed
US-20080299474-A1 HIGH QUALITY SUBSTITUTED ARYL DIAMINE AND A PHOTORECEPTOR XEROX CORPORATION (US) 2008-12-04 US claimed
EP-3859808-A1 AN ORGANIC ELECTRONIC DEVICE COMPRISING A HOLE INJECTION LAYER THAT COMPRISES A HOLE TRANSPORT COMPOUND Novaled GmbH (DE) 2021-08-04 EP disclosed
EP-3859811-A1 AN ORGANIC ELECTRONIC DEVICE COMPRISING AN ANODE LAYER, A CATHODE LAYER, AT LEAST ONE EMISSION LAYER (EML) AND AT LEAST ONE HOLE INJECTION LAYER (HIL) Novaled GmbH (DE) 2021-08-04 EP disclosed
US-20170075238-A1 FLUORINATED STRUCTURED ORGANIC FILM PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2017-03-16 US disclosed
US-20170075238-A1 FLUORINATED STRUCTURED ORGANIC FILM PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2017-03-16 US disclosed
US-9567425-B2 Periodic structured organic films XEROX CORPORATION (US) 2017-02-14 US disclosed
US-20170022338-A1 PERIODIC STRUCTURED ORGANIC FILMS XEROX CORPORATION 2017-01-26 US disclosed
US-20160259256-A1 IMAGING MEMBERS COMPRISING CAPPED STRUCTURED ORGANIC FILM COMPOSITIONS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2016-09-08 US disclosed
US-20160259256-A1 IMAGING MEMBERS COMPRISING CAPPED STRUCTURED ORGANIC FILM COMPOSITIONS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2016-09-08 US disclosed
EP-2098912-A1 Self-healing photoconductive member Xerox Corporation (US) 2009-09-09 EP disclosed
EP-2098913-A1 Photoconductive member Xerox Corporation (US) 2009-09-09 EP disclosed
US-20090220876-A1 SELF LUBRICATING PHOTORECEPTOR XEROX CORPORATION (US) 2009-09-03 US disclosed
EP-2083330-A1 Photoreceptor, method of making same and method of forming image using the same Xerox Corporation (US) 2009-07-29 EP disclosed
US-20090186287-A1 PHOTORECEPTOR AND METHOD OF MAKING SAME XEROX CORPORATION (US) 2009-07-23 US disclosed
US-20090130575-A1 PHOTORECEPTOR XEROX CORPORATION (US) 2009-05-21 US disclosed
US-20090117476-A1 PROTECTIVE OVERCOAT LAYER AND PHOTORECEPTOR INCLUDING SAME XEROX CORPORATION (US) 2009-05-07 US disclosed
US-20080299474-A1 HIGH QUALITY SUBSTITUTED ARYL DIAMINE AND A PHOTORECEPTOR XEROX CORPORATION (US) 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299474-A1 HIGH QUALITY SUBSTITUTED ARYL DIAMINE AND A PHOTORECEPTOR NR2E3, XPA, PRPH HRH3 26/4885LPL 3827/4885LIPG 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.