SCHEMBL6132937

SCHEMBL6132937

O=C1COC(c2ccccc2)OC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CYP2C19 P33261 1/20 0.54
KCNA4 P22459 1/20 0.44
KCNA1 Q09470 1/20 0.44
KCNAB1 Q14722 1/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 3/20 0.43
GAA P10253 1/20 0.43
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 2/20 0.40
POLB P06746 1/20 0.40
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
HTR2B P41595 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
AR P10275 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8079036 0.78 MEN1 (0.45) MEN1KMT2ACYP2C19KCNA4KCNA1
SCHEMBL8079031 0.78 MEN1 (0.45) MEN1KMT2ACYP2C19KCNA4KCNA1
SCHEMBL8079034 0.78 MEN1 (0.45) MEN1KMT2ACYP2C19KCNA4KCNA1
SCHEMBL27758818 0.77 MEN1 (0.48) MEN1KMT2ACYP2C19KCNA4KCNA1
SCHEMBL31546073 0.77 SLC6A4 (0.46) CYP3A4HTR2BKDM4E
SCHEMBL5946282 0.75 CYP2C19 (0.62) MEN1KMT2ACYP2C19KCNA4KCNA1
SCHEMBL366283 0.75 CYP2C19 (0.62) MEN1KMT2ACYP2C19KCNA4KCNA1
SCHEMBL9405189 0.74 TSHR (0.52) CYP2C19TSHRMAPTGAACYP1A2
Cyclohexane SCHEMBL28412113 0.74 MEN1 (0.46) MEN1KMT2ACYP2C19KCNA4KCNA1
SCHEMBL5432121 0.74 MEN1 (0.41) MEN1KMT2ACYP2C19KCNA4KCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101412706-A Novel method for preparing 1,3-dihydroxy acetone from glycerol UNIV ZHEJIANG TECHNOLOGY (CN) 2009-04-22 CN claimed
EP-0198388-A2 Enterally effective biologically active peptide or protein composition, method for the production thereof, and a pharmaceutical composition containing same Research Corporation (US) 1986-10-22 EP claimed
WO-2025027071-A1 MANUFACTURE OF POLYHYDROXYLAMINE VIA ELECTROLYSIS OF SUBSTRATES BRACCO IMAGING SPA (IT) 2025-02-06 WO disclosed
CN-109415334-B Process for producing 1, 3-dioxane-5-ones 花王株式会社 2023-12-08 CN disclosed
CN-111233817-B Oxidation method of glycerol acetal derivative 中国科学院大连化学物理研究所 2023-01-17 CN disclosed
CN-109641866-B Process for producing glycerate 花王株式会社 2022-02-25 CN disclosed
EP-3564226-B1 METHOD FOR PRODUCING GLYCERIC ACID ESTER KAO CORP (JP) 2021-06-02 EP disclosed
EP-3564226-B1 METHOD FOR PRODUCING GLYCERIC ACID ESTER KAO CORP (JP) 2021-06-02 EP disclosed
US-10870643-B2 Method for manufacturing 1,3-dioxane-5-one KAO CORPORATION (JP) 2020-12-22 US disclosed
US-10870643-B2 Method for manufacturing 1,3-dioxane-5-one KAO CORPORATION (JP) 2020-12-22 US disclosed
US-10822329-B2 Method for producing glyceric acid ester KAO CORPORATION (JP) 2020-11-03 US disclosed
CN-101412706-A Novel method for preparing 1,3-dihydroxy acetone from glycerol UNIV ZHEJIANG TECHNOLOGY (CN) 2009-04-22 CN disclosed
CN-101412706-A Novel method for preparing 1,3-dihydroxy acetone from glycerol UNIV ZHEJIANG TECHNOLOGY (CN) 2009-04-22 CN disclosed
US-6884868-B1 Cyclic hexapeptides having antibiotic activity FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2005-04-26 US disclosed
EP-1173472-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-23 EP disclosed
WO-2000064927-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 WO disclosed
US-4820811-A Amine reacted therapeutic agents RESEARCH CORPORATION (US) 1989-04-11 US disclosed
US-4654327-A PEPTIDES, PROTEINS AND ANTINEOPLASTIC DRUGS FOR ENTERNAL ADMINISTRATION RESEARCH CORP. (US) 1987-03-31 US disclosed
EP-0198388-A2 Enterally effective biologically active peptide or protein composition, method for the production thereof, and a pharmaceutical composition containing same Research Corporation (US) 1986-10-22 EP disclosed
US-4604376-A PROTEIN OR PEPTIDE AND SULFATE CORE WITH AMMONIUM ION RESEARCH CORPORATION (US) 1986-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10822329-B2 Method for producing glyceric acid ester GK, GRHPR, DGAT1 MEN1 2452/4885KMT2A 651/4885CYP2C19 850/4885
US-10870643-B2 Method for manufacturing 1,3-dioxane-5-one AOX1, HAO2, DUOX1 MEN1 1608/4885KMT2A 2233/4885CYP2C19 297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.