Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578019 | 1.00 | CYP2C19 (0.46) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL14612066 | 1.00 | CYP2C19 (0.46) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL14612067 | 1.00 | CYP2C19 (0.46) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL8079036 | 0.79 | MEN1 (0.45) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL8079031 | 0.79 | MEN1 (0.45) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL8079034 | 0.79 | MEN1 (0.45) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL22733776 | 0.74 | ALDH1A1 (0.46) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL22733775 | 0.74 | ALDH1A1 (0.46) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL980838 | 0.72 | ALDH1A1 (0.45) | CYP2C19CYP2C9TSHRGAAALDH1A1 | |
| SCHEMBL21553352 | 0.71 | CYP2C19 (0.80) | CYP2C19CYP2C9TSHRGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20060205816-A1 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205816-A1 | Chiral lactones | HSD11B2, HSD11B1, HSD17B2 | CYP2C19 190/4885CYP2C9 218/4885TSHR 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.