⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19795489 | 0.87 | PTPN1 (0.33) | — | |
| SCHEMBL1783224 | 0.82 | TAS1R3 (0.34) | — | |
| SCHEMBL1787702 | 0.80 | PTPN1 (0.33) | — | |
| SCHEMBL8082144 | 0.76 | SCN4A (0.31) | — | |
| SCHEMBL19795484 | 0.76 | PTPN1 (0.39) | — | |
| SCHEMBL19795471 | 0.73 | PTPN1 (0.37) | — | |
| SCHEMBL21662937 | 0.71 | PTPN1 (0.35) | — | |
| SCHEMBL14866840 | 0.69 | — | — | |
| SCHEMBL545418 | 0.69 | LOXL2 (0.33) | — | |
| SCHEMBL8069734 | 0.68 | GCGR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634403-B1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO SPA (IT) | 2000-09-13 | — | — | EP | disclosed |
| US-5541214-A | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.P.A. (IT) | 1996-07-30 | — | — | US | disclosed |
| EP-0634403-A1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.p.A. (IT) | 1995-01-18 | — | — | EP | disclosed |