Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795269 | 0.90 | EPHX2 (0.39) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL795752 | 0.87 | KMT2A (0.43) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL796276 | 0.78 | NPC1 (0.37) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL795333 | 0.77 | PIK3CA (0.41) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL807929 | 0.77 | ACHE (0.40) | GABRA5S1PR1ACHE | |
| SCHEMBL795379 | 0.77 | ALOX5AP (0.46) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL795751 | 0.76 | L3MBTL1 (0.45) | KMT2AALDH1A1MEN1GABRA5S1PR1 | |
| SCHEMBL15477140 | 0.75 | CHRNA7 (0.38) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL796172 | 0.75 | KMT2A (0.39) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL796285 | 0.75 | MAPT (0.36) | MAPTNPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |