Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073707 | 0.84 | KCNH2 (0.41) | — | |
| SCHEMBL8073971 | 0.81 | KDM4E (0.36) | POLBL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8074187 | 0.81 | POLB (0.34) | POLBL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8077099 | 0.81 | POLB (0.35) | POLBL3MBTL1RAB9ANPC1AKR1C3 | |
| SCHEMBL7756908 | 0.79 | ESRRG (0.35) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7760261 | 0.78 | — | — | |
| SCHEMBL8451929 | 0.78 | — | — | |
| SCHEMBL8073314 | 0.77 | PPARG (0.37) | POLBL3MBTL1RAB9ANPC1AKR1C3 | |
| SCHEMBL8920660 | 0.77 | NPC1 (0.35) | POLBL3MBTL1RAB9ANPC1AKR1C3 | |
| SCHEMBL8731527 | 0.76 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708106-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5650092-A | LIQUID CRYSTAL COMPOUNDS FOR DEVICES WITH ESTER COMPOUNDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0708106-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |