Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074187 | 0.84 | POLB (0.34) | POLBS1PR5S1PR1KMT2ANPC1 | |
| SCHEMBL8837098 | 0.80 | SLC6A2 (0.31) | — | |
| SCHEMBL8073707 | 0.79 | KCNH2 (0.41) | PPARGS1PR5S1PR1 | |
| SCHEMBL8079201 | 0.77 | POLB (0.37) | POLBNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7754206 | 0.77 | ESR2 (0.40) | — | |
| SCHEMBL8042329 | 0.77 | AOC3 (0.32) | — | |
| SCHEMBL8917063 | 0.76 | NPC1 (0.37) | POLBNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL8454705 | 0.76 | ALDH1A1 (0.33) | KMT2A | |
| SCHEMBL8073971 | 0.76 | KDM4E (0.36) | PPARGPOLBS1PR5KMT2ANPC1 | |
| SCHEMBL8077099 | 0.75 | POLB (0.35) | POLBKMT2ANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708106-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5650092-A | LIQUID CRYSTAL COMPOUNDS FOR DEVICES WITH ESTER COMPOUNDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0708106-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |