Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916577 | 0.93 | KDM4E (0.33) | KDM4ELMNAS1PR5KMT2AGAA | |
| SCHEMBL8073707 | 0.85 | KCNH2 (0.41) | S1PR5PPARG | |
| SCHEMBL8079201 | 0.81 | POLB (0.37) | LMNAGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8454689 | 0.81 | ALDH1A1 (0.33) | KMT2AALDH1A1MEN1 | |
| SCHEMBL7755500 | 0.79 | ESR2 (0.36) | — | |
| SCHEMBL8452872 | 0.79 | ALDH1A1 (0.34) | KDM4ELMNAKMT2AALDH1A1POLB | |
| SCHEMBL7758031 | 0.79 | KDM4E (0.32) | KDM4ELMNAGAAL3MBTL1MAPK1 | |
| SCHEMBL7759947 | 0.77 | RAB9A (0.34) | KDM4EALDH1A1POLBRAB9A | |
| SCHEMBL8077099 | 0.76 | POLB (0.35) | LMNAKMT2AGAAALDH1A1POLB | |
| SCHEMBL8920660 | 0.75 | NPC1 (0.35) | S1PR5KMT2AGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708106-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5650092-A | LIQUID CRYSTAL COMPOUNDS FOR DEVICES WITH ESTER COMPOUNDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0708106-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |