SCHEMBL8079448

SCHEMBL8079448

C=C(CSCCO)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
TET2 Q6N021 4/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
HPGD P15428 2/20 0.33
MAPT P10636 2/20 0.33
HSD17B10 Q99714 3/20 0.32
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2D6 P10635 1/20 0.32
HIF1A Q16665 1/20 0.32
ALDH1A1 P00352 2/20 0.31
USP2 O75604 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
GMNN O75496 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8070417 0.83 GMNN (0.42) MAPTHSD17B10GMNNTP53POLB
SCHEMBL8079419 0.80 TSHR (0.37) TSHR
SCHEMBL9250858 0.79 HSD17B10 (0.56) TDP1MAPTHSD17B10GRIK1GRIK2
SCHEMBL9983157 0.76 TDP1 (0.42) TDP1TET2TET3TET1HSD17B10
SCHEMBL6025408 0.76 THRB (0.53) TET2MAPTHSD17B10ALOX15ALDH1A1
SCHEMBL7900335 0.75 CYP2D6 (0.63) TDP1TET2TET3TET1MAPT
SCHEMBL11884507 0.74
SCHEMBL2558913 0.74
SCHEMBL4957174 0.73
Thiodiglycol SCHEMBL19987819 0.73 TDP1 (0.50) TDP1HPGDMAPTHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947402-B2 Solder mask inkjet inks for manufacturing printed circuit boards AFGA-GEVAERT NV (BE) 2021-03-16 US disclosed
EP-3321331-A1 SOLDER MASK INKJET INKS FOR MANUFACTURING PRINTED CIRCUIT BOARDS AGFA-GEVAERT (BE) 2018-05-16 EP disclosed
EP-0675885-B1 NOVEL RING OPENING MONOMERS COMMW SCIENT IND RES ORG (AU) 2000-09-06 EP disclosed
US-5665839-A Ring opening monomers COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1997-09-09 US disclosed
EP-0675885-A4 1995-10-25 EP disclosed
EP-0675885-A1 NOVEL RING OPENING MONOMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1995-10-11 EP disclosed
WO-1994014792-A1 NOVEL RING OPENING MONOMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1994-07-07 WO disclosed