Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BHMT | Q93088 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079448 | 0.79 | TDP1 (0.41) | HSD17B10LMNATDP1TSHRMAPT | |
| SCHEMBL7900335 | 0.78 | CYP2D6 (0.63) | HSD17B10LMNAKMT2ATDP1CYP2C19 | |
| Danosteine SCHEMBL1578704 | 0.78 | HSD17B10 (0.72) | HSD17B10LMNAKMT2ATDP1TSHR | |
| SCHEMBL12084188 | 0.78 | LMNA (0.72) | HSD17B10LMNAKMT2ATDP1TSHR | |
| SCHEMBL28562735 | 0.77 | LMNA (0.56) | HSD17B10LMNAKMT2ATDP1TSHR | |
| SCHEMBL11123745 | 0.75 | HSD17B10 (0.52) | HSD17B10LMNAKMT2ATDP1TSHR | |
| Danosteine SCHEMBL11664539 | 0.75 | HSD17B10 (0.68) | HSD17B10LMNAKMT2ATDP1TSHR | |
| E388 SCHEMBL28962323 | 0.74 | LMNA (1.00) | HSD17B10LMNAKMT2ATDP1TSHR | |
| E388 SCHEMBL28696 | 0.74 | LMNA (1.00) | HSD17B10LMNAKMT2ATDP1TSHR | |
| SCHEMBL6025408 | 0.74 | THRB (0.53) | HSD17B10TSHRMAPTALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675885-A4 | — | — | 1995-10-25 | — | — | EP | disclosed |
| EP-0675885-A1 | NOVEL RING OPENING MONOMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994014792-A1 | NOVEL RING OPENING MONOMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1994-07-07 | — | — | WO | disclosed |