Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507884 | 0.88 | DPP7 (0.50) | ANPEPRNPEPDNPEPSLC7A5DPP7 | |
| Bromide SCHEMBL7287179 | 0.85 | ANPEP (0.57) | ANPEPRNPEPDNPEPSLC7A5LARS1 | |
| SCHEMBL2322417 | 0.81 | ALDH1A1 (0.47) | ANPEPRNPEPDNPEPSLC7A5PSMB5 | |
| SCHEMBL11291910 | 0.81 | ALDH1A1 (0.47) | ANPEPRNPEPDNPEPSLC7A5PSMB5 | |
| SCHEMBL10659991 | 0.81 | SLC7A5 (0.42) | ANPEPRNPEPDNPEPSLC7A5PSMB5 | |
| SCHEMBL11291916 | 0.81 | ALDH1A1 (0.47) | ANPEPRNPEPDNPEPSLC7A5PSMB5 | |
| SCHEMBL1036014 | 0.81 | ALDH1A1 (0.47) | ANPEPRNPEPDNPEPSLC7A5PSMB5 | |
| SCHEMBL29006326 | 0.81 | ALDH1A1 (0.47) | ANPEPRNPEPDNPEPSLC7A5PSMB5 | |
| Hydrochloric Acid SCHEMBL10664913 | 0.80 | SLC7A5 (0.41) | ANPEPRNPEPDNPEPSLC7A5PSMB5 | |
| SCHEMBL7439605 | 0.79 | CACNA1B (0.42) | PSMB5MCL1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469693-A | 2-(4-Substituted alkyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives | AYERST, MCKENNA & HARRISON INC. (CA) | 1984-09-04 | — | — | US | claimed |
| EP-0722327-B1 | IMPROVEMENTS RELATING TO ANTIBACTERIAL COMPOSITIONS | UNILEVER PLC (GB) | 2000-11-22 | — | — | EP | disclosed |
| US-5639778-A | TREATING CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0722327-A1 | IMPROVEMENTS RELATING TO ANTIBACTERIAL COMPOSITIONS | UNILEVER PLC (GB) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009638-A1 | IMPROVEMENTS RELATING TO ANTIBACTERIAL COMPOSITIONS | UNILEVER PLC (GB) | 1995-04-13 | — | — | WO | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |