SCHEMBL8079519

SCHEMBL8079519

Cc1cc(O)c(C)c(N)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPT P10636 4/20 0.50
GAA P10253 4/20 0.50
ACHE P22303 1/20 0.43
HTT P42858 2/20 0.42
TSHR P16473 2/20 0.41
CASP1 P29466 1/20 0.41
PDE10A Q9Y233 1/20 0.41
CYP3A4 P08684 3/20 0.40
KDM4E B2RXH2 3/20 0.40
HSD17B10 Q99714 3/20 0.40
ALOX15 P16050 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
G6PD P11413 1/20 0.40
CYP2C9 P11712 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28959876 0.82 MAPT (0.48) ALDH1A1MAPTGAAACHEHTT
SCHEMBL9861927 0.82 ALDH1A1 (0.48) ALDH1A1MAPTGAAACHEHTT
Hydrochloric Acid SCHEMBL9861246 0.80 ALDH1A1 (0.52) ALDH1A1MAPTGAAACHEHTT
SCHEMBL395142 0.80 ALDH1A1 (0.47) ALDH1A1MAPTGAATSHRCASP1
SCHEMBL688980 0.79 ALDH1A1 (0.61) ALDH1A1MAPTGAAACHEHTT
SCHEMBL2741242 0.79 ALDH1A1 (0.50) ALDH1A1MAPTGAAACHEHTT
SCHEMBL14783927 0.78 ALDH1A1 (0.45) ALDH1A1MAPTGAAACHEHTT
Bromide SCHEMBL28821509 0.77 ALDH1A1 (0.45) ALDH1A1MAPTGAATSHRCASP1
Hydrochloric Acid SCHEMBL29008323 0.77 ALDH1A1 (0.45) ALDH1A1MAPTGAATSHRCASP1
Water SCHEMBL27673190 0.77 ALDH1A1 (0.45) ALDH1A1MAPTGAAHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454169-A Compositions comprising methylene malonate monomers and polymers, methods of making the same, and uses thereof in subterranean construction 巴斯夫欧洲公司 2021-09-28 CN claimed
CN-101649079-A Application of blend of resorcinol and m-aminophenol derivatives in rubber composition SINO LEGEND ZHANGJIAGANG CHEMI 2010-02-17 CN claimed
EP-1034321-A2 CORROSION-INHIBITING POLYSULFIDE SEALANTS H.B. Fuller Licensing & Financing, Inc. (US) 2000-09-13 EP claimed
WO-1999023280-A2 CORROSION-INHIBITING POLYSULFIDE SEALANTS H.B. FULLER LICENSING & FINANCING, INC. (US) 1999-05-14 WO claimed
EP-0145164-B1 PROCESS FOR IMPROVING MOISTURE RESISTANCE OR EPOXY RESINS BY ADDITION OF CHROMIUM IONS NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1987-03-04 EP claimed
CN-111752094-A Substrate with cured film, method for producing same, resin composition, cured film obtained by curing resin composition, and display device 日铁化学材料株式会社 2020-10-09 CN disclosed
CN-105742546-B Heat-resistant porous layer composition, separator comprising same, electrochemical cell using same, and method for manufacturing same 三星SDI株式会社 2019-09-06 CN disclosed
CN-109415646-A Lubricating additive composition, lubricating composition containing lubricating additive composition, and engine oil composition containing lubricating composition 株式会社ADEKA 2019-03-01 CN disclosed
CN-109153934-A Polyester dispersants, synthesis and application thereof 雪佛龙奥伦耐有限责任公司 2019-01-04 CN disclosed
CN-108139691-A Processing liquid and pattern forming method 富士胶片株式会社 2018-06-08 CN disclosed
CN-107735730-A developing solution, pattern forming method and manufacturing method of electronic device 富士胶片株式会社 2018-02-23 CN disclosed
CN-105408446-B The manufacture method of photochromic optical material 三井化学株式会社 2018-01-09 CN disclosed
US-4251426-A CORROSION AND CHIP RESISTANT COATINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-17 US disclosed
US-4189002-A Method for rigless zone abandonment using internally catalyzed resin system THE DOW CHEMICAL COMPANY (US) 1980-02-19 US disclosed
US-4069202-A ORGANIC DIBASIC ACID, TERTIARY AMINE SHELL OIL COMPANY (US) 1978-01-17 US disclosed
US-4040994-A OF A NON-FATTY POLYEPOXIDE COMPOUND, AT LEAST TWO EPOXIDIZED FATTY ACID ESTERS AND A POLYCARBOXYLIC ACID ANHYDRIDE CURING AGENT UNITECH CHEMICAL INC. (US) 1977-08-09 US disclosed
US-4017432-A TENSILE STRENGTH, ELONGATION SHELL OIL COMPANY (US) 1977-04-12 US disclosed
US-3977996-A CHROMIUM (III) CARBOXYLATE, COCATALYST AEROJET-GENERAL CORPORATION (US) 1976-08-31 US disclosed
US-3978026-A SYNERGISTIC, CHROMIUMIII TRICARBOXYLATE, COCATALYST AEROJET-GENERAL CORPORATION (US) 1976-08-31 US disclosed
US-3956241-A CHROMIUM(III) CHELATE COMPOUND AEROJET-GENERAL CORPORATION (US) 1976-05-11 US disclosed