SCHEMBL8079775

SCHEMBL8079775

CCCC(C(=O)O)(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
LMNA P02545 2/20 0.45
ALOX15 P16050 1/20 0.45
APEX1 P27695 1/20 0.45
MAPK1 P28482 1/20 0.45
RECQL P46063 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
KIF11 P52732 1/20 0.44
MMP9 P14780 1/20 0.44
MMP13 P45452 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
MAPT P10636 1/20 0.42
LDHA P00338 1/20 0.42
THRB P10828 1/20 0.42
ATM Q13315 1/20 0.42
HDAC3 O15379 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28271027 0.85 NPC1 (0.49) ALDH1A1LMNAALOX15APEX1MAPK1
SCHEMBL8631216 0.81 HSD17B10 (0.46) ALDH1A1LMNAALOX15APEX1MAPK1
SCHEMBL890797 0.80 ESR1 (0.57) ALDH1A1LMNAHSD17B10CA2CYP1A2
SCHEMBL1972152 0.80 MEN1 (0.49) ALDH1A1LMNAALOX15APEX1MAPK1
SCHEMBL14685859 0.80 PDE4B (0.51) ALDH1A1LMNAKIF11HDAC3HDAC1
SCHEMBL1614867 0.80 CYP2C19 (0.54) LMNAHSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL4878584 0.79 ALDH1A1 (0.49) ALDH1A1LMNAALOX15APEX1MAPK1
SCHEMBL11994174 0.79 KCNN4 (0.41) ALDH1A1LMNAAPEX1MAPK1HSD17B10
SCHEMBL3826995 0.79 ELANE (0.53) LMNAHSD17B10TDP1CA2MAPT
Hydrochloric Acid SCHEMBL2861649 0.78 CYP2C19 (0.55) ALDH1A1LMNAHSD17B10CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0862550-B1 CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE BASF AG (DE) 2000-11-08 EP disclosed
EP-0862550-A1 CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 1998-09-09 EP disclosed
WO-1997009294-A1 CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 1997-03-13 WO disclosed