Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 8/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078585 | 0.84 | ALDH1A1 (0.39) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL4821191 | 0.80 | EPHX2 (0.45) | MEN1KMT2AEPHX2 | |
| Hydrochloric Acid SCHEMBL8325862 | 0.79 | EPHX2 (0.44) | MEN1KMT2AEPHX2 | |
| Hydrochloric Acid SCHEMBL5523650 | 0.79 | EPHX2 (0.44) | MEN1KMT2AEPHX2 | |
| SCHEMBL13078578 | 0.75 | CACNA1B (0.37) | MEN1KMT2ACYP2D6 | |
| SCHEMBL14677777 | 0.75 | EPHX2 (0.39) | EPHX2 | |
| SCHEMBL28081696 | 0.75 | TSHR (0.42) | KMT2AEPHX2 | |
| SCHEMBL8088253 | 0.70 | ELOVL6 (0.47) | MEN1KMT2A | |
| SCHEMBL8091214 | 0.70 | DPP4 (0.39) | KCNH2CHRM1 | |
| SCHEMBL8079814 | 0.69 | HTT (0.46) | CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |