Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 16/20 | 0.47 |
| ▸ | PLA2G2E | Q9NZK7 | 3/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022769 | 0.81 | PLA2G1B (0.66) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL7010500 | 0.79 | PLA2G1B (0.55) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL7013828 | 0.78 | PLA2G1B (0.67) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL8024688 | 0.78 | PLA2G1B (0.57) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL7012767 | 0.75 | PLA2G2A (0.76) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL7010452 | 0.73 | PLA2G1B (0.73) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL9080332 | 0.72 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL7018295 | 0.71 | PLA2G1B (0.48) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL7018378 | 0.71 | PLA2G1B (0.73) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G10 | |
| SCHEMBL9307991 | 0.68 | HSPA5 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037630-A2 | METHOD FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH APOPTOSIS USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999024026-A2 | METHOD FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH APOPTOSIS USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |