Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070829 | 0.88 | FOLH1 (0.53) | FOLH1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL14870833 | 0.87 | FOLH1 (0.62) | FOLH1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL13643137 | 0.87 | FOLH1 (0.62) | FOLH1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL9158071 | 0.82 | FOLH1 (0.76) | FOLH1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL382849 | 0.82 | FOLH1 (0.62) | FOLH1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL11508209 | 0.81 | FOLH1 (0.74) | FOLH1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL4369735 | 0.81 | FOLH1 (1.00) | FOLH1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL14513595 | 0.81 | LDHA (0.55) | KDM4EALDH1A1MRGPRX4 | |
| SCHEMBL29179302 | 0.81 | FOLH1 (0.60) | FOLH1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL1647381 | 0.80 | FOLH1 (0.67) | FOLH1L3MBTL1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083987-A | 4-AMINO DERIVATIVE SUBSTITUTED PHENYLDIALKYLAMINE, USEFUL AS LIPID PEROXIDATION INHIBITOR | SHISEIDO CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |