Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14870833 | 1.00 | FOLH1 (0.62) | FOLH1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL13643136 | 0.88 | FOLH1 (0.48) | FOLH1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL14870834 | 0.88 | FOLH1 (0.48) | FOLH1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL8079907 | 0.87 | FOLH1 (0.68) | FOLH1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL14870838 | 0.86 | S1PR5 (0.53) | FOLH1ALDH1A1CTSVCTSLPTGER1 | |
| SCHEMBL13643141 | 0.86 | S1PR5 (0.53) | FOLH1ALDH1A1CTSVCTSLPTGER1 | |
| SCHEMBL18082677 | 0.84 | RXRA (0.49) | FOLH1ALDH1A1L3MBTL1PTGER1MRGPRX4 | |
| SCHEMBL14870836 | 0.83 | ERN1 (0.44) | FOLH1ALDH1A1KDM4EPTGER1FFAR4 | |
| SCHEMBL13643138 | 0.83 | ERN1 (0.44) | FOLH1ALDH1A1KDM4EPTGER1FFAR4 | |
| SCHEMBL13643146 | 0.82 | XDH (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | KIF5B, KIF2C, PLK1 | FOLH1 1919/4885ALDH1A1 2159/4885L3MBTL1 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.