SCHEMBL807996

SCHEMBL807996

c1ccc2c(c1)Oc1ccccc1N2c1ccc2c(c1)C1(c3ccccc3-c3ccccc31)c1ccccc1-2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 11/20 0.35
P2RX4 Q99571 5/20 0.33
MAPT P10636 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
OPRK1 P41145 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
SMAD3 P84022 1/20 0.30
PRMT1 Q99873 1/20 0.30
ACE2 Q9BYF1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14823503 0.95 P2RX4 (0.36) PDK2P2RX4MAPTSMN1; SMN2NPSR1
SCHEMBL14345607 0.93 MEN1 (0.34) PDK2P2RX4MAPTSMN1; SMN2MEN1
SCHEMBL21868270 0.92 MAPT (0.35) PDK2P2RX4MAPTSMN1; SMN2MEN1
SCHEMBL10039056 0.92 PDK2 (0.40) PDK2
SCHEMBL15183632 0.92 PDK2 (0.40) PDK2P2RX4MAPTSMN1; SMN2MEN1
SCHEMBL14823502 0.91 MAPT (0.35) PDK2P2RX4MAPTSMN1; SMN2MEN1
SCHEMBL23278290 0.91 PDK2 (0.30) PDK2
SCHEMBL15183639 0.91 PDK2 (0.41) PDK2MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL24647359 0.88 PDK2 (0.38) PDK2
SCHEMBL15183637 0.88 NPC1 (0.35) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023117836-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-29 WO disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-11024815-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-01 US disclosed
EP-3334731-B1 PHENOXAZINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-03-03 EP disclosed
EP-2826079-B1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-01-20 EP disclosed
EP-3210249-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-11-25 EP disclosed
US-10696664-B2 Phenoxazine derivatives for organic electroluminescent devices MERCK PATENT GMBH (DE) 2020-06-30 US disclosed
EP-3230402-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-04-15 EP disclosed
US-10454040-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2019-10-22 US disclosed
US-20150115239-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-04-30 US disclosed
EP-2616428-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-12-24 EP disclosed
WO-2014166572-A1 ORGANIC LIGHT-EMITTING DEVICE HAVING DELAYED FLUORESCENCE MERCK PATENT GMBH (DE) 2014-10-16 WO disclosed
WO-2014106521-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2014-07-10 WO disclosed
WO-2014106523-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2014-07-10 WO disclosed
WO-2014044344-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-03-27 WO disclosed
WO-2013135352-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2013-09-19 WO disclosed
US-20130207046-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130207046-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
WO-2012034627-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11024815-B2 Metal complexes EXOC4, EXOC3, TIMCC PDK2 3655/4885P2RX4 1106/4885MAPT 2450/4885
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES OCIAD2, AOC2, OCIAD1 PDK2 741/4885P2RX4 1820/4885MAPT 731/4885
US-10696664-B2 Phenoxazine derivatives for organic electroluminescent devices TYR, PPOX, SLCO2A1 PDK2 646/4885P2RX4 231/4885MAPT 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.