Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.56 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080763 | 0.89 | SOAT2 (0.57) | SOAT2ACAT1SOAT1ALDH1A1GLA | |
| SCHEMBL8049436 | 0.87 | SOAT2 (0.68) | SOAT2ACAT1SOAT1THRBPLK1 | |
| SCHEMBL8086038 | 0.84 | SOAT2 (0.59) | SOAT2ACAT1SOAT1PLK1ESR1 | |
| SCHEMBL8079670 | 0.84 | SOAT1 (0.79) | SOAT2ACAT1SOAT1ALDH1A1GLA | |
| SCHEMBL8080772 | 0.81 | SOAT2 (0.50) | SOAT2ACAT1SOAT1ALDH1A1GLA | |
| SCHEMBL8647324 | 0.81 | SOAT2 (0.38) | SOAT2ACAT1SOAT1ALDH1A1 | |
| SCHEMBL8042246 | 0.80 | SOAT2 (0.67) | SOAT2ACAT1SOAT1THRBPLK1 | |
| SCHEMBL8416104 | 0.80 | SOAT2 (0.67) | SOAT2ACAT1SOAT1PLK1ESR1 | |
| SCHEMBL8080878 | 0.79 | SOAT2 (0.48) | SOAT2ACAT1SOAT1ALDH1A1GLA | |
| SCHEMBL8043445 | 0.77 | SOAT2 (0.69) | SOAT2ACAT1SOAT1PLK1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871611-B1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PF MEDICAMENT (FR) | 2000-09-13 | — | — | EP | claimed |
| US-5760087-A | ANTICHOLESTEROL AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1998-06-02 | — | — | US | claimed |
| EP-0871611-B1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PF MEDICAMENT (FR) | 2000-09-13 | — | — | EP | disclosed |
| US-5760087-A | ANTICHOLESTEROL AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1998-06-02 | — | — | US | disclosed |