Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.79 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.79 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eflucimibe SCHEMBL668292 | 0.89 | SOAT2 (1.00) | SOAT1SOAT2ACAT1ALDH1A1CYP1A2 | |
| Eflucimibe SCHEMBL29427708 | 0.89 | SOAT2 (1.00) | SOAT1SOAT2ACAT1ALDH1A1CYP1A2 | |
| Eflucimibe SCHEMBL668294 | 0.89 | SOAT2 (1.00) | SOAT1SOAT2ACAT1ALDH1A1CYP1A2 | |
| SCHEMBL8080831 | 0.85 | SOAT2 (0.56) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL8080763 | 0.85 | SOAT2 (0.57) | SOAT1SOAT2ACAT1ALDH1A1PLK1 | |
| SCHEMBL8079964 | 0.84 | SOAT2 (0.56) | SOAT1SOAT2ACAT1ALDH1A1PLK1 | |
| Eflucimibe SCHEMBL8041449 | 0.80 | SOAT2 (0.82) | SOAT1SOAT2ACAT1ALDH1A1CYP1A2 | |
| SCHEMBL5900907 | 0.78 | SOAT2 (0.80) | SOAT1SOAT2ACAT1ALDH1A1CYP1A2 | |
| SCHEMBL5900910 | 0.78 | SOAT2 (0.80) | SOAT1SOAT2ACAT1ALDH1A1CYP1A2 | |
| SCHEMBL8080772 | 0.78 | SOAT2 (0.50) | SOAT1SOAT2ACAT1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871611-B1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PF MEDICAMENT (FR) | 2000-09-13 | — | — | EP | claimed |
| US-5760087-A | ANTICHOLESTEROL AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1998-06-02 | — | — | US | claimed |
| EP-0871611-B1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PF MEDICAMENT (FR) | 2000-09-13 | — | — | EP | disclosed |
| US-5760087-A | ANTICHOLESTEROL AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1998-06-02 | — | — | US | disclosed |