Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.64 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.57 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185966 | 0.98 | S1PR1 (0.67) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL9663932 | 0.98 | S1PR1 (0.67) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL11845832 | 0.98 | S1PR1 (0.67) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL2185272 | 0.98 | S1PR1 (0.67) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL7995811 | 0.97 | LMNA (0.71) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL16686916 | 0.95 | LMNA (0.69) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL9663920 | 0.95 | LMNA (0.69) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL7995339 | 0.95 | LMNA (0.69) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL8001563 | 0.95 | LMNA (0.69) | FFAR1L3MBTL1LMNAS1PR1S1PR3 | |
| SCHEMBL9259693 | 0.94 | S1PR1 (0.62) | FFAR1L3MBTL1LMNAS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048989-A | PARASITICIDES AND ANTIBROTOZOA AGENTS | WASHINGTON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| US-6025511-A | A MYRISTIC ACID SELECTED ANALOGS FOR INHIBITING THE BIOSYNTHESIS OF THE GLYCOSYL PHOSPHATIDYLINOSITOL (GPI) ANCHOR OF THE PARASITE | WASHINGTON UNIVERSITY (US) | 2000-02-15 | — | — | US | disclosed |
| US-6001869-A | CONTACTING THE PARASITE WITH 2-THIENYL-UNDECENOIC ACID/10-/ | WASHINGTON UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5998642-A | Thienyl-containing fatty acid glycosyl phosphatidylinosital analogues used for inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1999-12-07 | — | — | US | disclosed |