Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.62 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.62 |
| ▸ | RARB | P10826 | 7/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RARA | P10276 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185272 | 0.96 | S1PR1 (0.67) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL2185966 | 0.96 | S1PR1 (0.67) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL9663932 | 0.96 | S1PR1 (0.67) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL11845832 | 0.96 | S1PR1 (0.67) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL8080040 | 0.94 | FFAR1 (0.68) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL9663920 | 0.93 | LMNA (0.69) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL8001563 | 0.93 | LMNA (0.69) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL7995339 | 0.93 | LMNA (0.69) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL25175626 | 0.92 | S1PR1 (0.68) | S1PR1S1PR3S1PR4FFAR1LMNA | |
| SCHEMBL11309024 | 0.92 | S1PR1 (0.68) | S1PR1S1PR3S1PR4FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5417884-A | Containing a thiadiazole group | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-23 | — | — | US | disclosed |