Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.69 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.69 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005789 | 1.00 | LTB4R (0.69) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL1005790 | 1.00 | LTB4R (0.69) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL8080134 | 1.00 | LTB4R (0.69) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL8003031 | 0.98 | LTB4R (0.70) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL7999191 | 0.94 | LTB4R (0.65) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL8862104 | 0.94 | LTB4R (0.65) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL16710517 | 0.88 | NPC1 (0.65) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL1005998 | 0.87 | LTB4R (0.55) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL1005999 | 0.87 | LTB4R (0.55) | LTB4RLTB4R2PPARAFFAR1PPARG | |
| SCHEMBL1008121 | 0.85 | ALDH1A1 (0.56) | LTB4RLTB4R2PPARAFFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048989-A | PARASITICIDES AND ANTIBROTOZOA AGENTS | WASHINGTON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| US-6025511-A | A MYRISTIC ACID SELECTED ANALOGS FOR INHIBITING THE BIOSYNTHESIS OF THE GLYCOSYL PHOSPHATIDYLINOSITOL (GPI) ANCHOR OF THE PARASITE | WASHINGTON UNIVERSITY (US) | 2000-02-15 | — | — | US | disclosed |
| US-6001869-A | CONTACTING THE PARASITE WITH 2-THIENYL-UNDECENOIC ACID/10-/ | WASHINGTON UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5998642-A | Thienyl-containing fatty acid glycosyl phosphatidylinosital analogues used for inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5760259-A | MYRISTIC ACID DERIVATIVES CAPABLE OF INHIBITING BIOSYNTHESIS OF PARASITE'S ANCHORING GROUP | WASHINGTON UNIVERSITY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5747537-A | Method of inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1998-05-05 | — | — | US | disclosed |