Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.52 |
| ▸ | TFEB | P19484 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | F7 | P08709 | 2/20 | 0.48 |
| ▸ | F3 | P13726 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080171 | 1.00 | LTB4R (0.54) | LTB4RLTB4R2NFE2L2TFEBMAPT | |
| SCHEMBL3993752 | 0.88 | NFE2L2 (0.58) | NFE2L2TFEBMAPTLMNAKDM4E | |
| SCHEMBL3993756 | 0.88 | NFE2L2 (0.58) | NFE2L2TFEBMAPTLMNAKDM4E | |
| SCHEMBL10741731 | 0.87 | CYSLTR2 (0.57) | LTB4RLTB4R2MAPTLMNAKDM4E | |
| SCHEMBL10741724 | 0.87 | CYSLTR2 (0.57) | LTB4RLTB4R2MAPTLMNAKDM4E | |
| SCHEMBL10743272 | 0.83 | CYSLTR2 (0.58) | MAPTLMNAKDM4ECYSLTR2CYSLTR1 | |
| SCHEMBL10976574 | 0.83 | CYSLTR2 (0.58) | MAPTLMNAKDM4ECYSLTR2CYSLTR1 | |
| SCHEMBL10743270 | 0.83 | CYSLTR2 (0.58) | MAPTLMNAKDM4ECYSLTR2CYSLTR1 | |
| SCHEMBL6112991 | 0.82 | NFE2L2 (0.58) | LTB4RLTB4R2NFE2L2LMNAKDM4E | |
| SCHEMBL22560160 | 0.81 | LTB4R (0.47) | LTB4RLTB4R2NFE2L2TFEBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048989-A | PARASITICIDES AND ANTIBROTOZOA AGENTS | WASHINGTON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |