SCHEMBL8080247

SCHEMBL8080247

CCCCCCOc1ccccc1CC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
NR1I2 O75469 1/20 0.57
LMNA P02545 1/20 0.57
CHRM2 P08172 1/20 0.57
CYP3A4 P08684 1/20 0.57
ADRA2A P08913 1/20 0.57
MAPT P10636 1/20 0.57
OPRK1 P41145 1/20 0.57
HTR2B P41595 1/20 0.57
SLC6A3 Q01959 1/20 0.57
KMT2A Q03164 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
PPARG P37231 8/20 0.56
LTB4R Q15722 2/20 0.54
LTB4R2 Q9NPC1 1/20 0.54
CYSLTR2 Q9NS75 2/20 0.53
CYSLTR1 Q9Y271 2/20 0.53
PPARD Q03181 1/20 0.53
PPARA Q07869 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716918 1.00 MEN1 (0.57) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL8081517 1.00 MEN1 (0.57) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL10803242 1.00 MEN1 (0.57) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL8081126 1.00 MEN1 (0.57) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL8081501 1.00 MEN1 (0.57) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL8072236 1.00 MEN1 (0.57) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL2406964 0.98 PPARG (0.56) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL3485836 0.94 L3MBTL1 (0.55) MAPTPPARGLTB4RLTB4R2PPARD
SCHEMBL11738777 0.89 LMNA (0.59) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL8084869 0.89 L3MBTL1 (0.57) MEN1MAPTKMT2APPARGLTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed
CN-1128985-A Synthesis of substituted benzo [9, 10] phenanthrenes as discotic liquid crystals BRITISH TECH GROUP CO LTD (GB) 1996-08-14 CN disclosed
WO-1992009561-A1 NEW AMIDE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-06-11 WO disclosed
EP-0276064-A1 Anti-inflammatory agents ELI LILLY AND COMPANY (US) 1988-07-27 EP disclosed