SCHEMBL8080625

SCHEMBL8080625

CCCCC(C[NH])S(=O)(=O)CCCl

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.34
MMP7 P09237 3/20 0.34
MMP12 P39900 3/20 0.34
MMP13 P45452 3/20 0.34
ACE P12821 2/20 0.34
CA2 P00918 4/20 0.33
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8704234 0.81 CA2 (0.37) CA2TSHRTDP1
SCHEMBL9627604 0.81
SCHEMBL20306093 0.81 CA2 (0.43) CA2TSHR
SCHEMBL9628405 0.77
SCHEMBL8370376 0.73 CA2 (0.33) CA2
SCHEMBL9302683 0.71 CA2 (0.40) CA2TSHRTDP1
SCHEMBL391697 0.71 TP53 (0.39) MMP1MMP7MMP12MMP13ACE
SCHEMBL9628148 0.71
SCHEMBL8703184 0.67
SCHEMBL11045410 0.67 CA2 (0.50) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0703906-B1 FIBER REACTIVE ANTHRAQUINONE DYES DYSTAR L P (US) 2000-08-30 EP disclosed
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed
EP-0538785-B1 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AG (DE) 1997-04-09 EP disclosed
EP-0703906-A4 FIBER REACTIVE ANTHRAQUINONE DYES HOECHST CELANESE CORP (US) 1996-08-28 EP disclosed
EP-0703906-A1 FIBER REACTIVE ANTHRAQUINONE DYES HOECHST CELANESE CORPORATION (US) 1996-04-03 EP disclosed
US-5393884-A Water soluble blue dyes HOECHST CELANESE CORPORATION (US) 1995-02-28 US disclosed
US-5321134-A Water-soluble phthalocyanine dyes, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-14 US disclosed
US-5302708-A Colorfastness HOECHST AKTIENGESELLSCHAFT (DE) 1994-04-12 US disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0471702-B1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AG (DE) 1993-12-29 EP disclosed
US-5256776-A Brilliant green dyeings; fiber reactive HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5231172-A Water solubility HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed
US-5227475-A WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0541057-A1 Water-soluble phthalocyanine dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-12 EP disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
EP-0530660-A2 Water-soluble phthalocyanine dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-10 EP disclosed
EP-0527441-A2 Water-soluble phthalocyanine dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-17 EP disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed