SCHEMBL8370376

SCHEMBL8370376

CCCCCC(CCC[C]=O)S(=O)(=O)CCCl

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.30
GPR84 Q9NQS5 3/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754916 0.94 CA2 (0.30) CA2
SCHEMBL20306093 0.86 CA2 (0.43) CA2TP53GPR84
SCHEMBL8370377 0.76
SCHEMBL11045410 0.74 CA2 (0.50) CA2TP53GPR84
SCHEMBL8080625 0.73 MMP1 (0.34) CA2
SCHEMBL8704234 0.73 CA2 (0.37) CA2TP53
SCHEMBL9425828 0.69 LMNA (0.48) GPR84FFAR1
SCHEMBL24665741 0.68 DNM1 (0.46) CA2TP53GPR84FFAR1
SCHEMBL20988698 0.68 DNM1 (0.46) CA2TP53GPR84FFAR1
SCHEMBL20993783 0.68 DNM1 (0.46) CA2TP53GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5931975-A TRIAZINE REACTIVE DYES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-03 US disclosed
US-5925746-A HEAT RESISTANT DISAZO DYES WHICH PRODUCE COLORFAST PINK SHADES ON COTTON CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-20 US disclosed
EP-0889098-A2 Azo dyes, process for their preparation and the use thereof Ciba SC Holding AG (CH) 1999-01-07 EP disclosed
US-5684138-A Asymmetrical reactive dyes containing two triazinyl radicals which are bridged via an aliphatic bridge member CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-11-04 US disclosed
US-5679115-A APPLYING DYE TO FIBER WITH COLORLESS MATERIAL CONTAINING POLYMERIZABLE DOUBLE BOND, FIXING BY TREATING WITH IONIZING RADIATION CIBA-GEIGY CORPORATION (US) 1997-10-21 US disclosed
EP-0681623-B1 RADIATION-INDUCED FIXATION OF DYES CIBA GEIGY (CH) 1997-05-21 EP disclosed
EP-0629249-B1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES CIBA GEIGY AG (CH) 1997-01-08 EP disclosed
US-5552532-A Reactive dyes, processes for their preparation and their use CIBA-GEIGY CORPORATION (US) 1996-09-03 US disclosed
US-5525124-A IN PRESENCE OF REDUCED CONCENTRATION OF A MINERAL ACID SALT CIBA-GEIGY CORPORATION (US) 1996-06-11 US disclosed
US-5490866-A MIXTURE OF POLYVINYLPYRROLIDONE AND ALKALI SILICATE CIBA-GEIGY CORPORATION (US) 1996-02-13 US disclosed
EP-0681623-A1 RADIATION-INDUCED FIXATION OF DYES. CIBA GEIGY AG (CH) 1995-11-15 EP disclosed
EP-0629249-A1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES. CIBA GEIGY AG (CH) 1994-12-21 EP disclosed
WO-1994018381-A1 RADIATION-INDUCED FIXATION OF DYES CIBA-GEIGY AG (CH) 1994-08-18 WO disclosed
WO-1993018224-A1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES CIBA-GEIGY AG (CH) 1993-09-16 WO disclosed