Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402894 | 1.00 | LMNA (0.43) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL8080972 | 0.86 | — | — | |
| SCHEMBL2323889 | 0.82 | USP2 (0.34) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL7740976 | 0.78 | LMNA (0.46) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| Deoxyglucose SCHEMBL3019708 | 0.78 | LMNA (0.50) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| Deoxyglucose SCHEMBL10386937 | 0.78 | LMNA (0.50) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| Deoxyglucose SCHEMBL148114 | 0.78 | LMNA (0.50) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| Deoxyglucose SCHEMBL120125 | 0.78 | LMNA (0.50) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| Deoxyglucose SCHEMBL200714 | 0.78 | LMNA (0.50) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| Deoxyglucose SCHEMBL4480352 | 0.78 | LMNA (0.50) | LMNAL3MBTL1USP2SLCO1B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112076-A | ANTITUMOR ANTIBIOTICS | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1978-09-05 | — | — | US | disclosed |