Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.61 |
| ▸ | CTSS | P25774 | 2/20 | 0.61 |
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527895 | 0.85 | SYK (0.55) | CTSLCTSSCTSKCTRB1ATM | |
| SCHEMBL21333945 | 0.84 | CTSL (0.62) | CTSLCTSSCTSKSIRT2SIRT1 | |
| SCHEMBL28370653 | 0.84 | CTSL (0.62) | CTSLCTSSCTSKSIRT2SIRT1 | |
| SCHEMBL4126228 | 0.83 | CTSL (0.72) | CTSLCTSSCTSKSIRT2SIRT1 | |
| SCHEMBL11332452 | 0.83 | CTSL (0.72) | CTSLCTSSCTSKSIRT2SIRT1 | |
| SCHEMBL150166 | 0.83 | CTSL (0.72) | CTSLCTSSCTSKSIRT2SIRT1 | |
| SCHEMBL28414503 | 0.83 | CTSL (0.61) | CTSLCTSSCTSKSIRT2SIRT1 | |
| SCHEMBL5501379 | 0.83 | CTSL (0.61) | CTSLCTSSCTSKSIRT2SIRT1 | |
| SCHEMBL19021627 | 0.83 | CTSL (0.61) | CTSLCTSSCTSKSIRT2SIRT1 | |
| SCHEMBL15665360 | 0.82 | CTSL (0.70) | CTSLCTSSCTSKSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |