SCHEMBL8081667

SCHEMBL8081667

CC(=O)Oc1ccc2cc(OC(=O)c3cc(C(=O)Oc4ccc5cc(OC(C)=O)ccc5c4)cc(C(=O)Oc4ccc5cc(OC(C)=O)ccc5c4)c3)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.58
MEN1 O00255 4/20 0.58
MAPT P10636 4/20 0.58
TDP1 Q9NUW8 3/20 0.58
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
KDM4E B2RXH2 3/20 0.51
GLA P06280 1/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
FLT3 P36888 1/20 0.50
LMNA P02545 3/20 0.48
ESR1 P03372 1/20 0.48
CYP3A4 P08684 2/20 0.47
TTR P02766 1/20 0.47
TP53 P04637 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ELANE P08246 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24517581 0.91 KMT2A (0.61) KMT2AMEN1MAPTTDP1CA12
SCHEMBL8081490 0.90 LMNA (0.59) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL30595409 0.88 CA12 (0.65) KMT2AMEN1MAPTTDP1CA12
SCHEMBL3974361 0.88 CA12 (0.65) KMT2AMEN1MAPTTDP1CA12
SCHEMBL8081857 0.85 MAPT (0.67) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL16236336 0.84 KMT2A (0.84) KMT2AMEN1MAPTTDP1CA12
SCHEMBL12268652 0.84 MAPT (0.51) KMT2AMEN1MAPTTDP1CA12
SCHEMBL12925818 0.84 KMT2A (0.78) KMT2AMEN1MAPTTDP1CA12
SCHEMBL15462343 0.84 MAPT (0.51) KMT2AMEN1MAPTTDP1CA12
SCHEMBL5352558 0.84 CA12 (0.61) KMT2AMEN1MAPTTDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed