Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706963 | 0.85 | ALDH1A1 (0.48) | GAATSHRALDH1A1HSD17B10LMNA | |
| SCHEMBL2607864 | 0.82 | — | — | |
| SCHEMBL561195 | 0.82 | GAA (0.58) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL14534258 | 0.82 | MGAM (0.46) | MGAMGAASIMGAM2TSHR | |
| Methyl Alcohol SCHEMBL10632152 | 0.80 | GAA (0.56) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3037432 | 0.80 | MGAM (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5171320 | 0.80 | ALDH1A1 (0.43) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL10660310 | 0.79 | MGAM (0.42) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL11469977 | 0.79 | GAA (0.42) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL311876 | 0.79 | ALDH1A1 (0.53) | GAATSHRALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449580-B2 | Ticlopidine and clopidogrel simply prepared by reacting a substituted thiophene derivative with a 2-chlorobenzylamine derivative | HANMI PHARM. CO., LTD (KR) | 2008-11-11 | — | — | US | disclosed |
| US-20070197789-A1 | Method of preparing thieno[3,2-c]pyridine derivatives and intermediates used therein | HANMI PHARM, CO., LTD. | 2007-08-23 | — | — | US | disclosed |
| US-6121284-A | SPECIFIED 1-(ALKYL OR CYCLOALKYL)-2-METHYL-3-(ALKOXYCARBONYL)-4-(SUBSTITUTED PYRIDYL OR ARYL)-5-OXO-1,4,5,6,7,8-HEXAHYDROQUINOLINE COMPOUNDS; TREATING SICKLE CELL ANEMIA, PSYCHOSES, DEPRESSION | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| CN-1127250-A | 2,3-bridged 1,4-dihydropyridines, process for their preparation and their use as medicaments | BAYER AG (DE) | 1996-07-24 | — | — | CN | disclosed |
| EP-0245315-B1 | PROCESS FOR PREPARING $g(a)-HYDROXY CARBONYL COMPOUNDS | L. GIVAUDAN & CIE Société Anonyme (CH) | 1990-04-11 | — | — | EP | disclosed |
| US-4892966-A | FLAVORS FOR FOODS, TOBACCO | GIVAUDAN CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| US-4766213-A | 1,4-dihydropyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-08-23 | — | — | US | disclosed |
| EP-0245315-A1 | PROCESS FOR PREPARING -g(a)-HYDROXY CARBONYL COMPOUNDS. | GIVAUDAN & CIE SA (CH) | 1987-11-19 | — | — | EP | disclosed |
| US-4188395-A | 1,4-Dihydropyridine derivatives substituted in the 2 position, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197789-A1 | Method of preparing thieno[3,2-c]pyridine derivatives and intermediates used therein | PFKP, THPO, TBXA2R | MGAM 2715/4885GAA 2291/4885SI 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.