Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TTK | P33981 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15713879 | 0.94 | MEN1 (0.49) | ALDH1A1KDM4EHPGDGAAMAPK10 | |
| SCHEMBL1785972 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAAMAPK10 | |
| SCHEMBL10964298 | 0.79 | MAP2K4 (0.47) | ALDH1A1KDM4EHPGDGAAMAPK10 | |
| SCHEMBL4749775 | 0.75 | AKT2 (0.66) | MAPTNPSR1KMT2APDGFRBTP53 | |
| SCHEMBL18770477 | 0.75 | HSP90AA1 (0.44) | ALDH1A1KDM4EHPGDGAAMAPK10 | |
| SCHEMBL5231898 | 0.74 | KDM4E (0.62) | ALDH1A1KDM4EHPGDGAAMAPK10 | |
| SCHEMBL28146393 | 0.74 | ATM (0.43) | ALDH1A1KDM4EHPGDGAAMAPK10 | |
| SCHEMBL8011429 | 0.74 | RPS6KA3 (0.69) | ALDH1A1KDM4EHPGDGAARAB9A | |
| SCHEMBL27982550 | 0.74 | ABCC8 (0.63) | ALDH1A1KDM4EHPGDGAAMAPK10 | |
| SCHEMBL19926065 | 0.72 | GSK3A (0.57) | ALDH1A1KDM4EHPGDGAAMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121305-A | 5,5'-DIHYDROXY-4,4'-BIPYRAZOLE COMPOUNDS OF GIVEN FORMULA; FREE RADICAL SCAVENGER; USE TO TREAT CEREBRAL ISCHEMIA, HEART DISEASE, CARCINOMA, AGING, INFLAMMATION OR DIGESTIVE SYSTEM DISEASE, OR IN DETECTION OF AN ACTIVE OXYGEN OR FREE RADICALS | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |