Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080500 | 0.95 | NPC1 (0.44) | HTTTDP1THRBL3MBTL1MAPT | |
| SCHEMBL15582411 | 0.93 | HTT (0.41) | HTTRARBTDP1THRBL3MBTL1 | |
| SCHEMBL817059 | 0.91 | HTT (0.44) | HTTRARBTDP1THRBL3MBTL1 | |
| SCHEMBL15582407 | 0.91 | NPC1 (0.41) | HTTRARBTDP1THRBL3MBTL1 | |
| SCHEMBL8077196 | 0.90 | MAPT (0.38) | HTTTHRBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8080543 | 0.90 | MAPT (0.44) | HTTRARBTDP1THRBL3MBTL1 | |
| SCHEMBL14407739 | 0.89 | HTT (0.43) | HTTTDP1THRBL3MBTL1MAPT | |
| SCHEMBL21336504 | 0.88 | HTT (0.42) | HTTRARBTDP1THRBMAPT | |
| SCHEMBL12257778 | 0.88 | THRB (0.43) | HTTTDP1THRBL3MBTL1MAPT | |
| SCHEMBL8090334 | 0.88 | HTT (0.45) | HTTRARBTDP1THRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755918-B1 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | ROLIC AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| EP-0755918-A2 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | Rolic AG (CH) | 1997-01-29 | — | — | EP | disclosed |