Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082064 | 0.90 | MAPT (0.38) | MAPTKMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL8082089 | 0.90 | HTT (0.41) | MAPTALDH1A1CYP3A4TSHRTHRB | |
| SCHEMBL8077328 | 0.88 | MAPT (0.44) | MAPTKMT2AALDH1A1CYP3A4THRB | |
| SCHEMBL8080500 | 0.87 | NPC1 (0.44) | MAPTKMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL8067412 | 0.86 | XDH (0.43) | MAPTALDH1A1CYP3A4TSHRTHRB | |
| SCHEMBL8077319 | 0.86 | THRB (0.36) | MAPTKMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL8077403 | 0.86 | THRB (0.36) | MAPTKMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL8082091 | 0.86 | THRB (0.36) | MAPTKMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL8080583 | 0.86 | THRB (0.36) | MAPTKMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL8077222 | 0.86 | THRB (0.36) | MAPTKMT2AALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755918-B1 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | ROLIC AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| EP-0755918-A2 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | Rolic AG (CH) | 1997-01-29 | — | — | EP | disclosed |