Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013371 | 0.87 | MAPT (0.48) | ABCC4MAPTALDH1A1TSHRLMNA | |
| SCHEMBL11087650 | 0.84 | ALDH1A1 (0.43) | ABCC4MAPTALDH1A1TSHRLMNA | |
| SCHEMBL4017942 | 0.83 | MAPT (0.50) | ABCC4MAPTALDH1A1TSHRLMNA | |
| SCHEMBL16421159 | 0.81 | TSHR (0.57) | ABCC4MAPTALDH1A1TSHRLMNA | |
| SCHEMBL27039983 | 0.81 | MAPT (0.54) | ABCC4MAPTALDH1A1TSHRLMNA | |
| SCHEMBL14567209 | 0.79 | ABCC4 (0.47) | ABCC4MAPTALDH1A1TSHRLMNA | |
| SCHEMBL22367638 | 0.79 | ABCC4 (0.42) | ABCC4MAPTALDH1A1TSHRLMNA | |
| SCHEMBL1036461 | 0.78 | AKR1B1 (0.39) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9655594 | 0.78 | ABCC4 (0.41) | ABCC4MAPTALDH1A1TSHRLMNA | |
| SCHEMBL17954034 | 0.77 | ACLY (0.46) | ABCC4MAPTALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944659-B1 | METHOD FOR PRODUCING LINEAR BLOCK COPOLYMERS | BASF AG (DE) | 2000-10-18 | — | — | EP | disclosed |
| EP-0944659-A1 | METHOD FOR PRODUCING LINEAR BLOCK COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| EP-0693089-B1 | ORGANOSILICON-CONTAINING MATERIALS USEFUL FOR BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1998027127-A1 | METHOD FOR PRODUCING LINEAR BLOCK COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |
| US-5616757-A | CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1997-04-01 | — | — | US | disclosed |
| US-5510442-A | SOFT CONTACT LENSES; OXYGEN PERMEABILITY | BAUSCH & LOMB INCORPORATED (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0693089-A1 | ORGANOSILICON-CONTAINING MATERIALS USEFUL FOR BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024187-A2 | ORGANOSILICON-CONTAINING MATERIALS USEFUL FOR BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 1994-10-27 | — | — | WO | disclosed |
| US-4804756-A | Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4751304-A | Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0177256-A2 | Process for preparing 5,6-dialkoxy-4-alkyl-2(1h)-quinazolinones | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-04-09 | — | — | EP | disclosed |