Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15001325 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HPGDL3MBTL1APAF1POLB | |
| SCHEMBL2343419 | 0.78 | ALDH1A1 (0.40) | ALDH1A1POLBKDM4E | |
| SCHEMBL497418 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL4088521 | 0.76 | ALDH1A1 (0.39) | ALDH1A1POLBRECQLMEN1KMT2A | |
| SCHEMBL3392434 | 0.76 | ALDH1A1 (0.39) | ALDH1A1BLMKDM4E | |
| Hydrochloric Acid SCHEMBL17142804 | 0.74 | KDM4E (0.38) | ALDH1A1BLMMEN1KMT2AKDM4E | |
| SCHEMBL27257381 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5354462 | 0.72 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1POLBGRK2MEN1 | |
| SCHEMBL14938581 | 0.72 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1POLBGRK2MEN1 | |
| SCHEMBL7885120 | 0.72 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1POLBGRK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033968-A1 | ALPHA CARBOXYLIC ACID (AHA) DERIVATIVES | CECA S.A. (FR) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999056722-A1 | ALPHA CARBOXYLIC ACID (AHA) DERIVATIVES | CECA S.A. (FR) | 1999-11-11 | — | — | WO | disclosed |