Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420665 | 0.76 | POLB (0.36) | POLBALDH1A1 | |
| SCHEMBL6137753 | 0.71 | CA2 (0.34) | POLBALDH1A1 | |
| SCHEMBL7426969 | 0.70 | ALDH1A1 (0.54) | POLBALDH1A1 | |
| SCHEMBL27328134 | 0.70 | NPSR1 (0.41) | POLBALDH1A1 | |
| SCHEMBL4259665 | 0.70 | KMT2A (0.40) | POLBALDH1A1 | |
| SCHEMBL8082788 | 0.69 | — | — | |
| SCHEMBL437417 | 0.62 | NPSR1 (0.41) | ALDH1A1 | |
| SCHEMBL11682975 | 0.61 | SMN1; SMN2 (0.46) | ALDH1A1 | |
| SCHEMBL10661170 | 0.61 | POLB (0.52) | POLBALDH1A1 | |
| SCHEMBL28249141 | 0.61 | ALDH1A1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792291-B1 | PROTEIN AFFECTING KATP CHANNELS | UPJOHN CO (US) | 2000-09-20 | — | — | EP | disclosed |
| US-5925742-A | GLYCOPROTEIN OF 54,000 TO 60,000 DALTONS FROM RAT CELLS AND CAPABLE OF BINDING N-(3-AZIDO-5-IODOPHENYL)-N'-CYANO-N''-(1,1-DIMETHYLPROPYL)-GUANIDINE; MODULATORS OF ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNELS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-20 | — | — | US | disclosed |
| US-5856449-A | GLYCOPROTEIN | PHARMACIA & UPJOHN COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0792291-A1 | PROTEIN AFFECTING KATP CHANNELS | PHARMACIA & UPJOHN COMPANY (US) | 1997-09-03 | — | — | EP | disclosed |
| US-5525742-A | IDENTIFICATION OF BIOCHEMICAL COMPONENTS FORMING ATP-SENSITIVE POTASSIUM CHANNELS IN SMOOTH MUSCLE CELLS | THE UPJOHN COMPANY (US) | 1996-06-11 | — | — | US | disclosed |
| US-5525742-A | IDENTIFICATION OF BIOCHEMICAL COMPONENTS FORMING ATP-SENSITIVE POTASSIUM CHANNELS IN SMOOTH MUSCLE CELLS | THE UPJOHN COMPANY (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1996016088-A1 | PROTEIN AFFECTING KATP CHANNELS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-30 | — | — | WO | disclosed |