SCHEMBL8082829

SCHEMBL8082829

O=c1occn1-c1cccs1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.32
FGFR1 P11362 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9471238 0.69 TSHR (0.46) FGFR1
SCHEMBL4662853 0.67 CRBN (0.52) FGFR1
SCHEMBL11738105 0.66 ERCC1 (0.38) FGFR1
SCHEMBL5982117 0.65 BCHE (0.41)
SCHEMBL4794019 0.64 KMT2A (0.33) CHRNA7
SCHEMBL5822938 0.63 ADORA2A (0.36) FGFR1
SCHEMBL11128413 0.63 NPC1 (0.33) CHRNA7
SCHEMBL28469857 0.63 MGLL (0.44)
SCHEMBL4219701 0.62 ALDH1A1 (0.53) FGFR1
SCHEMBL905287 0.62 SMN1; SMN2 (0.44) FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111892528-B Preparation method of 7-amide indole compound 温州医科大学 2022-01-04 CN disclosed
CN-111892528-A Preparation method of 7-amide indole compound 温州医科大学 2020-11-06 CN disclosed
EP-1044214-A1 METHOD FOR BINDING ALBUMIN AND MEANS TO BE USED IN THE METHOD Amersham Pharmacia Biotech AB (SE) 2000-10-18 EP disclosed
US-5994507-A CONTACTING AQUEOUS LIQUID CONTAINING ALBUMIN WITH A COMPOUND CONTAINING THE SCAFFOLD--C(=O)-NH-C(=C-)-C(=O)- AND HAVING BEEN PRE-CHECKED TO BIND TO THE ALBUMIN; FOR REMOVAL OF ALBUMIN FROM A SOLUTION OR FOR PURIFICATION OF ALBUMIN AMERSHAM PHARMACIA BIOTECH AB (SE) 1999-11-30 US disclosed
WO-1999033860-A1 METHOD FOR BINDING ALBUMIN AND MEANS TO BE USED IN THE METHOD AMERSHAM PHARMACIA BIOTECH AB (SE) 1999-07-08 WO disclosed