SCHEMBL8082885

SCHEMBL8082885

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nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
PDE4A P27815 1/20 0.45
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
KDM4E B2RXH2 3/20 0.35
DUSP3 P51452 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.32
PRKCA P17252 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089557 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL24170112 0.84 PRKCA (0.41) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL5460546 0.84 PRKCA (0.41) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL19899603 0.83 LMNA (0.51) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL21066282 0.83 LMNA (0.51) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL3705601 0.83 LMNA (0.44) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL2673586 0.83 LMNA (0.44) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL20493977 0.83 LMNA (0.51) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL1287894 0.83 LMNA (0.44) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL4604786 0.83 LMNA (0.44) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054016-A1 Preparation of a mixture of glycosyl-mannitol and of glycosyl-sorbitol Roquette Frˬres (FR) 2000-11-22 EP disclosed