Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938136 | 0.78 | SMN1; SMN2 (0.43) | POLBRAB9A | |
| SCHEMBL5684577 | 0.77 | FFAR1 (0.49) | MAOBMAOASCN9AKCNN4PPARA | |
| SCHEMBL5684554 | 0.76 | TP53 (0.41) | MAOBMAOASCN9AKCNN4POLB | |
| SCHEMBL5684175 | 0.75 | MAOB (0.56) | MAOBMAOASCN9APARP10PPARA | |
| SCHEMBL1067948 | 0.73 | MAOB (0.65) | MAOBMAOASCN9APARP10PPARA | |
| SCHEMBL5536874 | 0.73 | MAOB (0.53) | MAOBMAOASCN9APARP10PPARA | |
| SCHEMBL5684098 | 0.71 | MAOB (0.53) | MAOBMAOASCN9APARP10PPARA | |
| SCHEMBL1654160 | 0.68 | NPC1 (0.39) | PARP10RAB9A | |
| SCHEMBL3970941 | 0.68 | FFAR1 (0.57) | MAOBMAOASCN9APPARA | |
| SCHEMBL29747227 | 0.67 | HCAR2 (0.60) | MAOBPARP10RAB9AHCAR2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044186-A1 | SUBSTITUTED 2-BENZYLAMINO-2-PHENYL-ACETAMIDE COMPOUNDS | Newron Pharmaceuticals S.p.A. (IT) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999035123-A1 | SUBSTITUTED 2-BENZYLAMINO-2-PHENYL-ACETAMIDE COMPOUNDS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 1999-07-15 | — | — | WO | disclosed |